A/Prof Jason Cain

BSc (Hons) PhD
Hudson Institute of Medical Research

A/Prof Jason Cain’s research focus is to understand the mechanisms underpinning the development and progression of childhood and adolescent solid tumours to identify novel therapeutic strategies to improve patient outcomes.   

A/Prof Jason Cain is head of the Developmental and Cancer Biology research group in the Centre of Cancer Research at the Hudson Institute of Medical Research. He is the inaugural My Room Children’s Cancer Charity Research Fellow and leads the My Room Children’s Cancer Charity Laboratory and Childhood and Adolescent Sarcoma Research Program. In 2023, A/Prof Cain was appointed Deputy Director of the Centre for Cancer Research at the Hudson Institute of Medical Research and as a Director of the Australia and New Zealand Sarcoma Association.  

After completing his BSc (2000), BSc(Hons) (2001) and PhD (2006) at Monash University, A/Prof Cain undertook his post-doctoral training at The Hospital for Sick Children in Toronto, Canada. Here, he focused on the role of the Hedgehog signalling pathway in development and disease, developing valuable and specialised skills in developmental biology, mouse models of human disease, and congenital and paediatric diseases. In 2010, he returned to Australia as a Research Fellow at the Monash Institute for Medical Research, now the Hudson Institute. Here, A/Prof Cain developed his current research program in childhood and adolescent cancer, focusing on sarcomas, combining a unique skill set of developmental and cancer biology expertise, techniques and concepts.  

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