Banking on a cure: Two biobanks receive funding boost to accelerate childhood cancer research

A/Prof Jason Cain
A/Prof Jason Cain
Deputy Director of the Hudson Institute's Centre for Cancer Research
November 6, 2025
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Every childhood cancer sample tells a story - one that could unlock new treatments, reveal hidden vulnerabilities in tumours, or guide personalised therapy for the next child diagnosed. Now, two biobanking initiatives promising to transform the study and treatment of rare childhood cancers have received a combined $770,000 in funding from Children's Cancer CoLab.

Biobanks are specialised repositories that collect, process, store and distribute biological samples, such as tumour tissue, blood and bone marrow, alongside clinical data. They serve as vital research infrastructure, providing scientists with the high-quality materials needed to study disease, test new discoveries, guide treatments for current patients, and advance precision medicine.

Monash Children's Cancer Centre: Supporting worldwide research

Established in 2011, the Monash Children's Cancer Biobank (MCCB) collects and stores samples from children with cancer for local and international research and to enhance the standard of care at Monash Health's Children's Cancer Centre. The biobank has experienced exponential growth, housing blood, bone marrow, cerebrospinal fluid, and tissue samples, and anticipates enrolling up to 200 new patients over the next two years.

A/Prof Peter Downie AM, Monash Children's Cancer Biobank Clinical Head, explains:

“Whilst also supporting researchers across the country, our biobank ensures that our patients can access precision medicine programs and clinical trials, while also contributing to research in Australia and internationally.”

Hudson Institute: Building living models of childhood cancer

The Hudson Institute of Medical Research Living Biobank is addressing a critical bottleneck in paediatric cancer research: the scarcity of accurate preclinical models that scientists can study in the laboratory.

A/Prof Jason Cain, the Living Biobank’s Lead Investigator, explains:

"Many childhood cancers are so rare that researchers simply don't have precise models to study them. Renewable patient-derived tumour models change that. They allow research teams around the world to test new therapies on a variety of childhood cancers, paving the way for more effective, targeted and less toxic treatments."

Using state-of-the-art technology, the Living Biobank creates these renewable models paired with clinical data, helping to accelerate the discovery of safer therapies that improve survival rates and enhance the quality and years of life for children diagnosed with cancer.

Funding to accelerate research, innovation and collaboration

CEO of Children's Cancer CoLab, Dr Udani Reets, said the two biobanks received funding through CoLab's Innovation Accelerators Impact Program, which supports streamlined technology platforms that foster multidisciplinary approaches for childhood cancer research.

“Funding these biobanks transforms precious samples donated by children and families into accessible resources for discovery. They will accelerate the pace of research, fulfilling the hopes of those families to help future generations of children not only survive cancer but thrive.”

Together, these biobanks represent a powerful investment in the future of childhood cancer care, where every sample preserved today could become tomorrow's breakthrough treatment.

Children's Cancer CoLab Impact Program grants are funded through a $35 million investment from the Victorian Government and a $10 million commitment from the Children's Cancer Foundation.

Learn more about the Hudson Institute Living Biobank, which has received a $410,162 CoLab grant.

Learn more about the Monash Children's Cancer Biobank, which has received a $360,000 CoLab grant.

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All stories published by Children’s Cancer CoLab can be shared under a Creative Commons Attribution-Non Commercial 4.0 International license, which means you're welcome to share and adapt our content with proper attribution using the details below.

A/Prof Jason Cain
Deputy Director of the Hudson Institute's Centre for Cancer Research
Jennie Do
Laboratory Manager and Technical Specialist
Maxwell Moraleda
Manager of the Hudson Institute Living Biobank
Amanda St. John
Clinical Research Team Lead at Monash Health’s Children’s Cancer Centre and co-investigator of Monash Children’s Cancer Biobank
Dilru Habarakada
Biobank Scientific Lead for Monash Children’s Cancer Biobank
A/Prof Peter Downie AM
Monash Children's Cancer Biobank Clinical Head

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Your support drives critical research and innovation that will change lives. By supporting Children's Cancer CoLab, you become part of a community working to ensure every young patient with cancer survives and thrives. Our approach unites top researchers across disciplines and institutions, breaking traditional barriers to accelerate discoveries from the lab to clinic, creating real impact for young cancer patients and their families.