Dr Enid Lam is a Senior Postdoctoral Researcher and Bioinformatician in the Cancer Epigenetics Laboratory at the Peter MacCallum Cancer Centre. She leads advanced bioinformatic analyses of next generation sequencing datasets to investigate normal and malignant haematopoiesis and mechanisms of therapeutic resistance. Her research focuses on developing and applying computational pipelines for single cell and bulk RNA seq, ATAC seq, ChIP seq and CRISPR screens, with a particular emphasis on integrating single cell multi omics with lineage tracing approaches to dissect regulatory and developmental dynamics in haematopoietic cells. This integrative, multi modal strategy underpins her current work and enables high resolution characterisation of cellular states, trajectories, and epigenetic mechanisms relevant to malignant transformation and treatment response.
Dr Lam’s background spans molecular biology, bioinformatics, and genomic technologies. Her earlier work includes studies of haematopoietic stem cell development in zebrafish, as well as the development of genome wide methods to map non canonical G quadruplex DNA structures at Cambridge University. Her research has been supported by a Victorian Cancer Agency mid career fellowship and multiple NHMRC project, Ideas, and Synergy grants.
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